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Mary’s Medicinals

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“Cannabis is not ‘alternative medicine,’ it is an alternative to medicine.” For many cannabis is a gray area, but for Mary’s Medicinals it is completely black and white. Mary’s Medicinals is a cannabusiness inspired by the forefathers and generations of healers who achieved relief and healing through nature. Each product combines turn-of-the-century elegance with the modern-day resurgence of natural therapies. Mary’s Medicinals is best known for the award-winning transdermal patch, a perfect example of science and horticulture merged. Mary’s Medicinals line of cannabis products transform the way patients of all walks of life view and use hemp and marijuana, creating products that maximize the benefits of cannabinoids, terpenes, and plant nutrients. History Mary’s Medicinals was established in April of 2013 in Denver, Colorado. Since the launch of Mary’s Medicinals, the team has relentlessly pushed the barriers of medicinal cannabis delivery methods by discovering and implementing new products that reshape the conventions of cannabis use. Mary’s consistent development of innovative cannabis products earned her brand many accolades. The Cannabis Business Awards awarded Mary’s Medicinals’ Elite Patch the Invention of the Year in 2014, and Mary took home the award for Most Innovative Product at the CannAwards and Best New Product at High Times’ Cannabis Cup. Today, you can find Mary’s Medicinals in 10 states across the US, with more to come as the brand grows. The team strives to deliver all-natural wellness solutions into the hands of patients who need it most. Process Mary’s Medicinals is comprised of a team of experts who pioneer unorthodox delivery and extraction methods and combine nutritionals that work synergistically with cannabinoids to ease patient’s pain effectively. Chief Scientist of Mary’s Medicinals Dr. Jeremy Riggle, Ph.D. collaborates with his team to bring its groundbreaking products to life. Mary’s Medicinals sources its flowers from a network of local, trusted, high-quality cannabis gardens with master growers that practice absolute quality control. Then, the starting material sourced from long-standing partners are processed by Mary’s expert extraction artists to produce best-in-class transdermal patches, cannabis vape cartridges, topicals, and concentrates. Products Mary presents effective products that are accurately dosed and derived from clean, lab-tested cannabis flowers. Mary’s Medicinals is best known for its transdermal patches; the Elite Patch is a 2-inch x 2-inch laser-cut square containing 10 mg of active THC. Simply apply the latex-free, hypoallergenic, pharmaceutical grade adhesive to your skin, and the active cannabinoids are released gradually over 8 to 12 hours. Mary’s Medicinal transdermal patch comes in CBD options as well, giving patients access to non-intoxicating and extremely discreet relief. Mary’s Medicinals’ vape cartridges are offered in 1:1 CBN:CBD, 3:1 CBD:THC and a pure THC blend.  Drip a drop of relief with The Remedy, a line of cannabis and hemp derived tinctures. The Remedy comes in 200 mg, 1:1 CBD: THC as well as 500 mg of pure THC or CBD. From soil to the final product, Mary upholds industry-leading accountability motivated by her patient-first values. Lab Testing The Mary’s Medicinals team takes the safety and efficacy of its medical cannabis products to heart, and are proud to offer lab-tested medical cannabis products. Mary’s Medicinal quarterly tests its products through BotaniCore for cannabinoid and terpene content, microbials, and pesticides.

Mary’s Medicinals Cannabis CBD, Topicals & Tinctures

12 products

A Quick Guide to CBD Products

CBD (cannabidiol) is the second most-studied cannabinoid in cannabis after THC — and unlike THC, it's non-intoxicating. You can take CBD throughout the day without experiencing a high, which is why it's become one of the most popular cannabinoid formats for daily wellness use. Common applications include sleep support, anxiety reduction, post-exercise recovery, joint inflammation, and chronic pain management.

CBD products come in three formulations that consumers should understand. Full-spectrum CBD includes all naturally-occurring cannabinoids and terpenes from the source plant, including trace THC (under 0.3%). Broad-spectrum contains the same compounds minus THC. Isolate is 99%+ pure CBD with no other cannabinoids. Many users find full-spectrum more effective due to the "entourage effect" — the theory that whole-plant compounds work better together than CBD alone. Isolate appeals to those who need to avoid any THC exposure (drug testing, sensitivities).

Effective CBD doses vary widely by individual. Many people find relief at 10–25mg for relaxation and sleep; chronic pain or anxiety can require 50–200mg. CBD has a long half-life (18–32 hours), so consistent daily dosing builds steady cannabinoid levels — most people give a routine 1–2 weeks before judging effectiveness. CBD also interacts with the liver enzymes that metabolize many prescription medications (similar to grapefruit juice), so consult your doctor if you take prescription drugs. Atrium carries CBD tinctures, capsules, edibles, topicals, and pet products from California's most-trusted CBD brands.

About CBD Products

What is CBD?

CBD (cannabidiol) is the second most-studied cannabinoid in cannabis after THC. Unlike THC, CBD is non-intoxicating — it won't produce a high. CBD is used for sleep, anxiety, inflammation, pain, and seizures (the FDA has approved a CBD medication for certain epilepsy disorders).

What's the difference between CBD from hemp and CBD from cannabis?

Chemically, the CBD molecule is identical. The difference is legal status and the source plant. Hemp-derived CBD (less than 0.3% THC) is federally legal under the 2018 Farm Bill. Cannabis-derived CBD (sold at California dispensaries) often contains higher CBD concentrations and may include legal THC for a full-spectrum experience.

What's the difference between full-spectrum, broad-spectrum, and isolate CBD?

Full-spectrum contains all cannabinoids including up to 0.3% THC. Broad-spectrum contains multiple cannabinoids but no THC. Isolate is 99%+ pure CBD with no other cannabinoids. Many users find full-spectrum more effective due to the entourage effect, while isolate appeals to those avoiding any THC exposure.

Will CBD show up on a drug test?

Pure CBD isolate should not trigger a positive drug test — standard tests look for THC metabolites, not CBD. Full-spectrum CBD contains trace THC (under 0.3%), which can accumulate with daily heavy use and potentially trigger a positive test. If you're subject to testing, choose isolate or broad-spectrum products.

How much CBD should I take?

Effective doses vary widely — 10–25mg works for many people for relaxation and sleep; higher doses (50–200mg) may be needed for chronic pain or anxiety. Start with the lowest dose on the label, take it consistently for 1–2 weeks, and adjust based on results. CBD is generally well-tolerated even at high doses.

When does CBD work best?

CBD has a relatively long half-life (18–32 hours), so daily consistent dosing builds steady levels. Many users take CBD in the morning for daytime relaxation or in the evening for sleep. Sublingual tinctures act fastest (15–45 min); capsules and edibles take longer (60–120 min) but last longer.

Are there side effects of CBD?

CBD is generally well-tolerated. Mild side effects can include drowsiness, dry mouth, diarrhea, or appetite changes — usually at high doses. CBD can interact with medications metabolized by liver enzymes (the same as grapefruit juice), so consult your doctor if you take prescription drugs.

What's the difference between THC and CBD?

THC is the primary intoxicating cannabinoid — it activates CB1 receptors in the brain to produce the cannabis high. CBD doesn't bind directly to CB1 receptors; instead, it modulates the endocannabinoid system more broadly and is non-intoxicating. Many people use them together — CBD softens THC's anxiety potential while preserving therapeutic effects.

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